IDRC Laboratories

Welcome to the Infectious Diseases Research Collaboration (IDRC) Laboratories, home to the Molecular Research Laboratory (MOLAB), Butabika Laboratory, and the Tororo Research Laboratory (TOLAB). Our state-of-the-art facilities support Uganda’s clinical and laboratory research projects and surveillance programs. 

Translation research is at the core of our laboratories’ functions, focusing on bridging the gap between scientific discoveries and their practical application in clinical practice or public health interventions. We engage in various research activities, including basic science, clinical studies, biomarker discovery, drug development, technology development, and data analysis. 

Ensuring the accuracy and reliability of research findings is paramount, which is why our laboratories prioritise quality control and assurance. This commitment to excellence guarantees that subsequent clinical translation and implementation are successful. 

Our laboratories foster collaboration among scientists from various disciplines, including biologists, chemists, physicists, and clinicians. This multidisciplinary approach enhances the quality and breadth of research, allowing for a comprehensive understanding of complex health issues. 

Let’s take a closer look at each of our facilities: 

Molecular Research Laboratory (MOLAB)

Situated on the campus of Mulago Hospital, MOLAB is the central hub of the IDRC laboratories. It plays a vital role in capacity building for biomedical scientists and is renowned as the centre of malaria microscopy in Uganda. MOLAB conducts various assays, including genotyping of parasites, monitoring drug resistance assays, and culturing malaria parasites. 

Tororo Research Laboratory (TOLAB) 

Established in Tororo District, TOLAB focuses on molecular studies, culturing malaria parasites, and conducting translational research in molecular, parasitology, and immunology studies. With state-of-the-art facilities, TOLAB ensures efficient sample storage, computerised databases, generator power backup, and high-speed internet access. 

Butabika Laboratory

Based at the Central Public Laboratory in Butabika, the IDRC genomic laboratory primarily studies the genome of Plasmodium falciparum, the parasite causing malaria. Our research focuses on understanding genetic variations related to malaria parasite drug resistance. Advanced techniques such as real-time PCR, DNA sequencing, and bioinformatics are employed to achieve these goals. Additionally, immunology-specialised assays explore antibody responses to malaria antigens. 

Overall, our laboratories, including MOLAB, contribute significantly to Uganda’s research and understanding of malaria. We strive to improve human health and well-being through cutting-edge research and the application of knowledge gained. These facilities play a crucial role in turning scientific discoveries into tangible benefits for individuals and society as a whole.